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9 岁女孩接种乙型肝炎疫苗后发生视神经炎。

Optic neuritis following hepatitis B vaccination in a 9-year-old girl.

机构信息

Goztepe Educational and Research Hospital, Istanbul, Turkey.

出版信息

J Chin Med Assoc. 2009 Nov;72(11):594-7. doi: 10.1016/S1726-4901(09)70435-6.

DOI:10.1016/S1726-4901(09)70435-6
PMID:19948437
Abstract

Hepatitis B vaccination can prevent hepatitis B virus infection and its serious consequences, including liver cancer and cirrhosis. Serious side effects reported after receiving hepatitis B vaccination are very uncommon. A majority of the ophthalmological complications seen following hepatitis B vaccination consist of vision loss, optic neuritis, papillary edema, uveitis, acute placoid pigment epitheliopathy and central vein occlusion. We present a 9-year-old girl who was referred to our hospital with decrease in vision and pain in the left eye a week after hepatitis B vaccination. A diagnosis of vaccine-induced optic neuritis was made. The clinical picture improved after systemic corticosteroid treatment. Acute optic neuritis might be a rare complication of hepatitis B vaccination. Parents should be aware of the potential serious side effects of the vaccine.

摘要

乙肝疫苗接种可以预防乙肝病毒感染及其严重后果,包括肝癌和肝硬化。接种乙肝疫苗后报告的严重副作用非常罕见。乙肝疫苗接种后出现的大多数眼科并发症包括视力丧失、视神经炎、乳头水肿、葡萄膜炎、急性盘状色素上皮病变和中央静脉阻塞。我们现介绍 1 例 9 岁女孩,在接种乙肝疫苗 1 周后因左眼视力下降和疼痛就诊于我院。诊断为疫苗诱导的视神经炎。全身皮质类固醇治疗后临床症状改善。急性视神经炎可能是乙肝疫苗接种的罕见并发症。家长应了解疫苗的潜在严重副作用。

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