Institute for Innovative Learning, Mahidol University, Bangkok, Thailand.
Adv Physiol Educ. 2009 Dec;33(4):297-301. doi: 10.1152/advan.00036.2009.
From our teaching of the contractile unit of the striated muscle, we have found limitations in using textbook illustrations of sarcomere structure and its related dynamic molecular physiological details. A hand-held model of a striated muscle sarcomere made from common items has thus been made by us to enhance students' understanding of the sliding filament mechanism as well as their appreciation of the spatial arrangements of the thick and thin filaments. The model proves to be quite efficacious in dispelling some alternative conceptions held by students exposed previously only to two-dimensional textbook illustrations and computer graphic displays. More importantly, after being taught by this hand-held device, electronmicrographic features of the A and I bands, H zone, and Z disk can be easily correlated by the students to the positions of the thick and thin elements relatively sliding past one another. The transverse expansion of the sarcomere and the constancy of its volume upon contraction are also demonstrable by the model.
从我们教授横纹肌的收缩单位的经验来看，我们发现使用教科书中关于肌节结构及其相关动态分子生理细节的插图存在局限性。因此，我们制作了一个由常见物品制成的手持式横纹肌肌节模型，以增强学生对滑行丝机制的理解以及对粗丝和细丝空间排列的欣赏。事实证明，该模型非常有效地消除了学生以前仅通过二维教科书插图和计算机图形显示所获得的一些替代概念。更重要的是，通过这个手持设备进行教学后，学生可以轻松地将 A 带和 I 带、H 带和 Z 盘的电子显微镜特征与相对滑动的粗丝和细丝元素的位置相关联。该模型还可以证明肌节的横向扩张和收缩时其体积的恒定性。
