Department of Orthopaedic Surgery, Research Institute of Clinical Medicine, Chonbuk National University School of Medicine, Jeonju, Korea.
Spine (Phila Pa 1976). 2009 Dec 15;34(26):2886-92. doi: 10.1097/BRS.0b013e3181b64f2c.
STUDY DESIGN.: Retrospective study. OBJECTIVE.: To compare the efficacy of anterior cervical discectomy and fusion with cage alone (ACDF-CA) with cage and plate construct (ACDF-CPC) in regards to fusion rate, radiologic and clinical outcomes. SUMMARY OF BACKGROUND DATA.: ACDF-CA has shown good results; however, debate exists regarding the high rate of complications such as pseudarthrosis, subsidence, and local kyphosis. In an attempt to avoid these complications, the authors have performed ACDF with cage and plate construct (ACDF-CPC). METHODS.: A total of 78 consecutive patients who underwent 1- or 2-level ACDF-CA or ACDF-CPC suffering from cervical radiculopathy were divided into 2 groups; Group A (n = 38) underwent ACDF-CA; Group B (n = 40) underwent ACDF-CPC. Fusion rate, segmental kyphosis, disc height, and subsidence rate were assessed by radiographs. Clinical outcomes were assessed using Robinson criteria. RESULTS.: Solid fusion was achieved in 78.9% (30/38) of subjects in group A compared to 97.5% (39/40) of subjects in group B (P = 0.01). Segmental kyphosis was noted in 42.1% (16/38) in group A compared with 10% (4/40) in group B (P < 0.01). There was a significant decrease in disc height in group A compared to group B (P < 0.05). Subsidence occurred in 32.3% (19/59 levels) of group A compared with 9.7% (6/62 levels) of group B (P < 0.01). Clinical outcomes were similar for both treatment groups. The pseudarthrosis rate in group A was higher than that in group B (P = 0.01). Revision surgery was required in 10.5% (4/38) of group A, whereas none of group B required reoperation (P < 0.01). CONCLUSION.: The use of cage and plate construct in 1- or 2-level ACDF results in a more lordotic alignment, an increased disc height, a higher fusion rate, a lower subsidence rate, and a lower complication rate than that of cage alone; however, there is no significant difference in clinical outcome between groups.
回顾性研究。
比较单纯颈椎前路椎间盘切除融合术(ACDF-CA)与颈椎前路椎间盘切除融合术加钢板固定(ACDF-CPC)在融合率、影像学和临床结果方面的疗效。
ACDF-CA 已显示出良好的效果;然而,关于并发症如假关节形成、下沉和局部后凸的高发生率仍存在争议。为了避免这些并发症,作者采用了颈椎前路椎间盘切除融合术加钢板固定(ACDF-CPC)。
共纳入 78 例因神经根型颈椎病行单节段或双节段 ACDF-CA 或 ACDF-CPC 的连续患者,分为两组;A 组(n=38)行 ACDF-CA;B 组(n=40)行 ACDF-CPC。通过 X 线评估融合率、节段性后凸、椎间盘高度和下沉率。采用 Robinson 标准评估临床结果。
A 组 38 例中有 78.9%(30/38)达到了坚固融合,而 B 组 40 例中有 97.5%(39/40)达到了坚固融合(P=0.01)。A 组中有 42.1%(16/38)出现节段性后凸,而 B 组中仅有 10%(4/40)出现节段性后凸(P<0.01)。与 B 组相比,A 组的椎间盘高度明显降低(P<0.05)。A 组中有 32.3%(19/59 个节段)发生下沉,而 B 组中有 9.7%(6/62 个节段)发生下沉(P<0.01)。两组治疗的临床结果相似。A 组的假关节发生率高于 B 组(P=0.01)。A 组中有 10.5%(4/38)需要翻修手术,而 B 组中无一例需要再次手术(P<0.01)。
在 1 或 2 个节段的 ACDF 中使用钢板固定可使颈椎获得更前凸的排列、增加椎间盘高度、提高融合率、降低下沉率和降低并发症发生率,但其临床结果与单纯使用钢板固定无显著差异。