Division of Hepatology, Department of Internal Medicine, Dankook University College of Medicine, Cheonan, Korea.
J Korean Med Sci. 2009 Dec;24(6):1195-9. doi: 10.3346/jkms.2009.24.6.1195. Epub 2009 Nov 9.
Phlebosclerotic colitis is a rare form of ischemic colitis characterized by the thickening of the wall of the affected colon due to fibrous degeneration of submucosal layer of colon and fibrotic obstruction of the colono-mesenteric vein, resulting in the disturbance of venous return from the colon. The pathogenic mechanism of this entity remains unknown but chronic liver disease with portal hypertension is maybe thought to be one of the speculated mechanisms. Here we first report the case of surgically confirmed phlebosclerotic colitis, that was in the early stage but showed the aggressive nature, in a 61-yr-old cirrhotic patients with portal hypertension in Korea.
静脉性硬化性结肠炎是一种罕见的缺血性结肠炎，其特征为结肠黏膜下层的纤维变性和结肠肠系膜静脉的纤维性阻塞导致受累结肠的壁增厚，从而扰乱了结肠的静脉回流。该实体的发病机制尚不清楚，但慢性肝病伴门静脉高压症可能被认为是推测的机制之一。在这里，我们首次报告了一例在韩国的 61 岁肝硬化伴门静脉高压症患者中，手术证实的处于早期阶段但表现出侵袭性的静脉性硬化性结肠炎病例。
