Department of Psychiatry, Adnan Menderes University, Aydin, Türkiye.
Int J Eat Disord. 2010 Dec;43(8):766-9. doi: 10.1002/eat.20783.
A 16-year-old girl was admitted to the emergency department because of acute changes in mental state such as paranoid and nihilistic delusions, confabulations, and distortions of body schema perception. Her history was compatible with anorexia nervosa in that she had lost more than 17 kg in weight over one and a half years. Her body mass index was 14. She was diagnosed with Wernicke Korsakoff's syndrome and was given intravenous thiamine at 250 mg/day. Response was dramatic for nystagmus and gait incoordination but not for other symptoms. After dosage was increased to 750 mg/day all symptoms including psychosis improved. With her increase in food consumption, secondary deterioration was observed and diagnosed as refeeding syndrome. After proper replacements she was completely normal in the 9th month, and her weight was 55 kg. This patient was interesting for the presenting symptoms (psychosis), and improvement by high doses of thiamine replacement, and also for refeeding syndrome during this period.
一位 16 岁女孩因精神状态急性改变，如妄想、虚构、身体感知扭曲等，被收入急诊科。她的病史与神经性厌食相符，在一年半的时间里体重减轻了超过 17 公斤。她的体重指数为 14。她被诊断为 Wernicke-Korsakoff 综合征，并给予每天 250 毫克的静脉注射硫胺素。她的眼球震颤和步态不协调症状有明显改善，但其他症状没有改善。当剂量增加到 750 毫克/天时，包括精神病在内的所有症状都有所改善。随着她食物摄入量的增加，出现了继发性恶化，并被诊断为再喂养综合征。经过适当的治疗后，她在第 9 个月完全恢复正常，体重为 55 公斤。这个病人的症状（精神病）、高剂量硫胺素替代治疗的改善以及在此期间发生的再喂养综合征都很有趣。
