在孟加拉国的一项基于人群的研究中，黑热病后皮肤利什曼病的发病率不断增加。
Increasing incidence of post-kala-azar dermal leishmaniasis in a population-based study in Bangladesh.
机构信息
International Centre for Diarrhoeal Disease Research, Bangladesh.
出版信息
Clin Infect Dis. 2010 Jan 1;50(1):73-6. doi: 10.1086/648727.
Post-kala-azar dermal leishmaniasis (PKDL) occurs after kala-azar treatment and acts as a durable infection reservoir. On the basis of active case finding among 22,699 respondents, 813 (3.6%) had had kala-azar since 2002, of whom 79 (9.7%) developed PKDL. Eight additional patients with PKDL had no history of kala-azar. Annual kala-azar incidence peaked at 85 cases per 10,000 person-years in 2004 and fell to 46 cases per 10,000 person-years in 2007, but PKDL incidence rose from 1 case per 10,000 person-years in 2002-2004 to 21 cases per 10,000 person-years in 2007. The rising PKDL incidence threatens the regional visceral leishmaniasis elimination initiative and underscores the urgent need for more effective PKDL diagnosis and treatment.
黑热病后皮肤利什曼病（PKDL）发生在黑热病治疗后，是一个持久的感染储库。在对 22699 名应答者进行主动病例发现的基础上，自 2002 年以来有 813 人（3.6%）患有黑热病，其中 79 人（9.7%）发生了 PKDL。另外 8 名患有 PKDL 的患者没有黑热病病史。黑热病年发病率在 2004 年达到每 10000 人年 85 例的峰值，随后下降到 2007 年的每 10000 人年 46 例，但 PKDL 发病率从 2002-2004 年的每 10000 人年 1 例上升到 2007 年的每 10000 人年 21 例。不断上升的 PKDL 发病率威胁到该地区的内脏利什曼病消除倡议，突显了迫切需要更有效的 PKDL 诊断和治疗。
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