Kang Won Hyoung, Kim Yun Jeon, Pyo Won Sik, Park Sung Jin, Kim Jie Hoon
Department of Dermatology, College of Medicine, Kwan-Dong University, Ilsan, Korea.
J Cosmet Laser Ther. 2009 Dec;11(4):212-5. doi: 10.3109/14764170903134326.
Atrophic scars are a common complication of acne. Many modalities are proposed but each does not yield satisfactory clinical outcomes. Thus, a new combination therapy is suggested that incorporates (i) dot peeling, the focal application and tattooing of higher trichloroacetic acid concentrations; (ii) subcision, the process by which there is separation of the acne scar from the underlying skin; and (iii) fractional laser irradiation. In this pilot study, the efficacy and safety of this method was investigated for the treatment of acne scars. Ten patients received this therapy for a year. Dot peeling and subcision were performed twice 2-3 months apart and fractional laser irradiation was performed every 3-4 weeks. Outcomes were assessed using scar severity scores and patients' subjective ratings. Acne scarring improved in all of the patients completing this study. Acne scar severity scores decreased by a mean of 55.3%. Eighty percent of the patients felt significant or marked improvement. There were no significant complications at the treatment sites. It would appear that triple combination therapy is a safe and very effective combination treatment modality for a variety of atrophic acne scars.
萎缩性瘢痕是痤疮的常见并发症。虽然提出了多种治疗方法,但每种方法都未产生令人满意的临床效果。因此,有人提出一种新的联合治疗方法,包括:(i)点状剥脱,即局部应用高浓度三氯乙酸并进行纹身;(ii)皮下分离,即痤疮瘢痕与下方皮肤分离的过程;(iii)分次激光照射。在这项初步研究中,对该方法治疗痤疮瘢痕的疗效和安全性进行了调查。10名患者接受了为期一年的这种治疗。点状剥脱和皮下分离每隔2 - 3个月进行两次,分次激光照射每3 - 4周进行一次。使用瘢痕严重程度评分和患者主观评分来评估结果。所有完成本研究的患者的痤疮瘢痕均有改善。痤疮瘢痕严重程度评分平均下降了55.3%。80%的患者感觉有显著或明显改善。治疗部位未出现明显并发症。三联联合治疗似乎是一种安全且非常有效的治疗多种萎缩性痤疮瘢痕的联合治疗方式。