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1550纳米铒玻璃点阵激光与皮肤瘢痕化学重建(CROSS)方法治疗痤疮瘢痕的比较:一项同步双侧面部试验

Comparison of a 1,550 nm Erbium: glass fractional laser and a chemical reconstruction of skin scars (CROSS) method in the treatment of acne scars: a simultaneous split-face trial.

作者信息

Kim Hee Jung, Kim Tae Gyun, Kwon Yeon Sook, Park Jin Mo, Lee Ju Hee

机构信息

Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.

出版信息

Lasers Surg Med. 2009 Oct;41(8):545-9. doi: 10.1002/lsm.20796.

Abstract

BACKGROUND AND OBJECTIVE

Acne scarring is a common complication of acne but no effective single treatment modality has been developed. To compare the efficacy of 1,550 nm Er:Glass fractional laser and chemical reconstruction of skin scar (CROSS) method in the treatment of acne scars.

STUDY DESIGN/MATERIALS AND METHODS: A split-face trial was conducted in 20 patients (10 rolling, 10 icepick types) with acne scars. One side was treated with the 1,550 nm Er:Glass fractional laser three times with a 6-week interval. And the other side was treated with CROSS method two times every 12 weeks.

RESULTS

Significant improvement was observed in both sides of the face. In rolling type, the objective and subjective improvement rates were significantly higher in the sides treated with laser than CROSS method. However, in icepick type, there were no statistically significant differences between the two treatment sides. In the laser sides, grades of pain were significantly higher than that of treated with CROSS method. However, downtimes and lasting days of erythema were significantly longer in the sides treated with CROSS method.

CONCLUSION

A 1,550 nm Er:Glass fractional laser and CROSS method are both well-tolerated and effective treatment options in the acne scars. However, there was a relatively small difference between the two treatment modalities. Therefore, dermatologists should consider the acne scar type to select the treatment options. Lasers Surg. Med. 41:545-549, 2009. (c) 2009 Wiley-Liss, Inc.

摘要

背景与目的

痤疮瘢痕是痤疮常见的并发症,但尚未开发出有效的单一治疗方式。比较1550nm铒玻璃飞梭激光与皮肤瘢痕化学重建(CROSS)方法治疗痤疮瘢痕的疗效。

研究设计/材料与方法:对20例痤疮瘢痕患者(10例为滚轮状,10例为冰锥状)进行了半脸试验。一侧用1550nm铒玻璃飞梭激光治疗3次,间隔6周。另一侧每12周用CROSS方法治疗2次。

结果

面部两侧均观察到显著改善。在滚轮状瘢痕类型中,激光治疗侧的客观和主观改善率显著高于CROSS方法治疗侧。然而,在冰锥状瘢痕类型中,两种治疗侧之间无统计学显著差异。在激光治疗侧,疼痛等级显著高于CROSS方法治疗侧。然而,CROSS方法治疗侧的红斑持续时间和恢复时间显著更长。

结论

1550nm铒玻璃飞梭激光和CROSS方法都是治疗痤疮瘢痕耐受性良好且有效的选择。然而,两种治疗方式之间差异相对较小。因此,皮肤科医生应根据痤疮瘢痕类型选择治疗方案。《激光外科与医学》41:545 - 549,2009年。(c)2009威利 - 利斯公司。

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