Sunohara Mitsuhiro, Hara Kei, Osamura Kou, Tashiro Naoki, Shibuya Hideki, Nakahara Kazuki, Kishida Yukiko, Tamura Kouichi, Hisada Tetsuya
Department of Respiratory Medicine, Tokyo Teishin Hospital, Tokyo, Japan.
Intern Med. 2009;48(23):2025-32. doi: 10.2169/internalmedicine.48.2424. Epub 2009 Dec 1.
Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) of the thymus is rare and little is known about its karyotype abnormality. MALT lymphoma in general shows a good prognosis, but some reports suggest that the presence of trisomy 18 predicts recurrence. Here, we report a patient with MALT lymphoma of the thymus and the left parotid gland accompanied by Sjogren's syndrome. The karyotype analysis revealed that this is the first case of thymic MALT lymphoma with trisomy 18, which we believe is worth reporting. We also review cases with thymic MALT lymphoma previously reported in the literature.
胸腺黏膜相关淋巴组织结外边缘区淋巴瘤（MALT淋巴瘤）较为罕见，其核型异常情况鲜为人知。一般来说，MALT淋巴瘤预后良好，但一些报告表明18号染色体三体的存在预示着复发。在此，我们报告1例伴有干燥综合征的胸腺及左腮腺MALT淋巴瘤患者。核型分析显示，这是首例伴有18号染色体三体的胸腺MALT淋巴瘤病例，我们认为值得报道。我们还回顾了文献中先前报道的胸腺MALT淋巴瘤病例。
