Stanford, Palo Alto, and San Francisco, Calif. From the Department of Surgery, Division of Plastic Surgery, and the Department of Ophthalmology and Hansen Experimental Physics Laboratory, Stanford University, PEAK Surgical, Inc., and the Department of Pathology and Laboratory Medicine, University of California, San Francisco.
Plast Reconstr Surg. 2009 Dec;124(6):1849-1859. doi: 10.1097/PRS.0b013e3181bcee87.
The PEAK PlasmaBlade is a new electrosurgical device that uses pulsed radiofrequency to generate a plasma-mediated discharge along the exposed rim of an insulated blade, creating an effective cutting edge while the blade stays near body temperature.
Full-thickness incisions were made on the dorsums of pigs with the PlasmaBlade, a conventional electrosurgical device, and a scalpel, and blood loss was quantified. Wounds were harvested at designated time points, tested for wound tensile strength, and examined histologically for scar formation and tissue damage.
Bleeding was reduced significantly (59 percent) in PlasmaBlade incisions compared with scalpel incisions, and acute thermal damage from the PlasmaBlade (66 +/- 5 microm) was significantly less than both cut and coagulation mode electrosurgical incisions (456 +/- 35 microm and 615 +/- 22 microm, respectively). Histologic scoring for injury and wound strength was equivalent between the PlasmaBlade and scalpel incisions. By 6 weeks, the healed PlasmaBlade and scalpel incisions were approximately three times stronger, and scar cosmetic appearance was significantly better compared with electrosurgical incisions.
The PlasmaBlade is a promising new surgical instrument that provides atraumatic, scalpel-like cutting precision and electrosurgical-like hemostasis, resulting in minimal bleeding, tissue injury, and scar formation.
PEAK PlasmaBlade 是一种新型的电外科设备，它使用脉冲射频在绝缘刀片的暴露边缘产生等离子介导的放电，从而在刀片保持接近体温的情况下形成有效的切割边缘。
使用 PlasmaBlade、传统电外科设备和手术刀在猪的背部进行全层切口，定量测量出血量。在指定的时间点采集伤口，测试伤口的拉伸强度，并进行组织学检查以评估疤痕形成和组织损伤。
与手术刀切口相比，PlasmaBlade 切口的出血明显减少（减少 59%），而 PlasmaBlade 产生的急性热损伤（66±5 微米）明显小于切割和凝血模式的电外科切口（分别为 456±35 微米和 615±22 微米）。PlasmaBlade 和手术刀切口的组织损伤和伤口强度的组织学评分相当。6 周后，愈合的 PlasmaBlade 和手术刀切口的强度约为电外科切口的三倍，疤痕的美容外观明显优于电外科切口。
PlasmaBlade 是一种有前途的新型手术器械，它提供了类似手术刀的无创伤切割精度和电外科的止血效果，从而减少出血、组织损伤和疤痕形成。
