Şahin Ömer Faruk, Uzlu Oğuzhan, Tunç Bekir, Yılmaz Ali, Yapakcı Mağruf İlkay, Gürpınar Ahmet B
Department of Neurosurgery, Ordu University Faculty of Medicine, Ordu, Turkey.
Department of Biochemistry, Tokat Gaziosmanpaşa University, Tokat, Turkey.
Med Sci Monit. 2025 May 31;31:e948722. doi: 10.12659/MSM.948722.
BACKGROUND This study compares the effects of monopolar electrocautery and blunt dissection on muscle damage, inflammatory response, and bleeding control in lumbar microdiscectomy surgery. This retrospective study aimed to compare the outcomes of muscle damage (creatine kinase (CK), lactate dehydrogenase levels (LDH)), inflammation (C-reactive protein levels [CRP]), and intraoperative bleeding (hemoglobin). MATERIAL AND METHODS Seventy-two patients (36 in each group) who underwent single-level lumbar microdiscectomy between 2021 and 2023 were retrospectively analyzed. In group A, the fascia and multifidus muscle were opened with electrocautery, and in group B, the fascia was opened with scalpel/Matzenbaum, and blunt dissection was performed with a periosteal elevator. CK, LDH, CRP, and hemoglobin levels were measured preoperatively and at 1 and 24 h. Statistical analyses used t test, Mann-Whitney U test, and repeated measures ANOVA. RESULTS CK levels at 24 h were significantly higher in group B (P<0.05). CRP levels at 1 h were significantly higher in group A (P=0.003). Hemoglobin decrease was greater in group B. There was no significant difference in LDH levels. CONCLUSIONS In our study, monopolar electrocautery was associated with less muscle damage, while a more pronounced inflammatory response was observed. Electrocautery provided better intraoperative bleeding control.
背景 本研究比较了单极电灼术和钝性分离术对腰椎间盘显微切除术患者肌肉损伤、炎症反应及出血控制的影响。这项回顾性研究旨在比较肌肉损伤(肌酸激酶[CK]、乳酸脱氢酶水平[LDH])、炎症(C反应蛋白水平[CRP])及术中出血(血红蛋白)的情况。材料与方法 回顾性分析2021年至2023年间接受单节段腰椎间盘显微切除术的72例患者(每组36例)。A组用电灼术切开筋膜和多裂肌,B组用手术刀/马曾鲍姆剪刀切开筋膜,并用骨膜剥离子进行钝性分离。在术前、术后1小时和24小时测量CK、LDH、CRP及血红蛋白水平。统计分析采用t检验、曼-惠特尼U检验和重复测量方差分析。结果 B组术后24小时的CK水平显著更高(P<0.05)。A组术后1小时的CRP水平显著更高(P=0.003)。B组的血红蛋白下降幅度更大。LDH水平无显著差异。结论 在我们的研究中,单极电灼术造成的肌肉损伤较小,但炎症反应更明显。电灼术在术中出血控制方面效果更佳。