[遗传和环境因素对儿童内化行为的影响：一项双胞胎研究]
[The effect of genetic and environmental factors on the internalizing behavior of children: a twin study].
作者信息
Situ Mingjing, Li Tao, Gao Xin, Zhang Xiaowei, Fang Hui, Zhang Yi, Huang Yi
机构信息
Department of Psychiatry, West China Hospital, Sichuan University, Chengdu, ichuan, 610041 PR China.
出版信息
Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2009 Dec;26(6):639-43. doi: 10.3760/cma.j.issn.1003-9406.2009.06.007.
OBJECTIVE
To investigate the impacts of genetic and environmental factors on the internalizing behaviors of children using quantitative genetic analysis designed for twin study.
METHODS
One hundred and eighty nine twin pairs aged 6-16 years were studied using parental information of Achenbach Child Behavior Checklist, Family Adaptability and Cohesion Evaluation Scales-II and General Health Questionnaire-12. The heritability of the internalizing behavior of children was also estimated.
RESULTS
(1) The heritability of the internalizing behavior of the children was 0.54, which differed in different age and sex. (2) Family adaptability and parental mental health status had significant correlation with the internalizing behavior of children (r=-0.213, 0.250, 0.309, respectively, Ps <0.001),especially the mental health status of the mother (OR=2.483, P=0.008).
CONCLUSION
The internalizing behavior of children was influenced by genetic and environmental factors including family function and parental mental health status. It differed in different age and sex.
目的
采用双生子研究的定量遗传学分析方法，探讨遗传和环境因素对儿童内化行为的影响。
方法
使用阿肯巴克儿童行为量表、家庭适应性和凝聚性评估量表-II以及一般健康问卷-12的父母信息，对189对6至16岁的双胞胎进行研究。同时估计儿童内化行为的遗传度。
结果
（1）儿童内化行为的遗传度为0.54，在不同年龄和性别中存在差异。（2）家庭适应性和父母心理健康状况与儿童内化行为显著相关（相关系数分别为-0.213、0.250、0.309，P值均<0.001），尤其是母亲的心理健康状况（比值比=2.483，P=0.008）。
结论
儿童的内化行为受遗传和环境因素影响，包括家庭功能和父母心理健康状况，且在不同年龄和性别中存在差异。
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