Department of Chemistry, University of Sheffield, Brook Hill, Sheffield S3 7HF, UK.
Org Lett. 2010 Jan 1;12(1):160-3. doi: 10.1021/ol902573x.
The in situ generation of alkynyldifluoroboranes in the presence of N-heterocycle substituted tetrazines provides a convenient and direct method for the synthesis of pyridazine difluoroboranes. The reactions proceed in 10 min under ambient conditions and provide the opportunity to assemble unsymmetrical products with complete regiocontrol.
在 N-杂环取代的四嗪存在下原位生成炔基二氟硼烷，为合成哒嗪二氟硼烷提供了一种方便、直接的方法。反应在环境条件下 10 分钟内进行，并提供了完全区域控制的组装不对称产物的机会。
