Geltner D, Cernik-Harush H, Ayzenberg O
Department of Internal Medicine, Kaplan Hospital, Rehovot, Israel.
Isr J Med Sci. 1991 Jan;27(1):5-7.
In order to establish the association between mitral valve prolapse (MVP) and the incidence of thromboembolic disease of the brain we reassessed 36 patients (less than or equal to 50 years old) who were hospitalized during 1983-85 because of cerebrovascular accidents. The patients underwent complete physical and neurological examinations, blood tests including coagulogram and two-dimensional echocardiogram. The control group comprised 117 patients without cerebrovascular events. In the study group, 4 patients (11.1%) had MVP compared with 10 (8.5%) in the control group. Of these four, only one male did not have any risk factor for thromboembolic event; among the other three the risk factors were systemic lupus erythematosus, hyperlipidemia, diabetes, hypertension and pregnancy. We conclude that our results are in accordance with most of the literature that MVP is not a risk factor for thromboembolic disease except in Greek and Italian populations, which are ethnically more homogeneous than other Western societies studied.
为了确定二尖瓣脱垂（MVP）与脑栓塞性疾病发病率之间的关联，我们重新评估了36例（年龄小于或等于50岁）在1983年至1985年期间因脑血管意外住院的患者。这些患者接受了全面的体格检查和神经检查、包括凝血图在内的血液检查以及二维超声心动图检查。对照组包括117例无脑血管事件的患者。在研究组中，4例（11.1%）有MVP，而对照组为10例（8.5%）。在这4例患者中，只有1名男性没有任何血栓栓塞事件的危险因素；在其他3例中，危险因素包括系统性红斑狼疮、高脂血症、糖尿病、高血压和妊娠。我们得出结论，我们的结果与大多数文献一致，即除了希腊和意大利人群（与所研究的其他西方社会相比，种族更为单一）外，MVP不是血栓栓塞性疾病的危险因素。
