Namiki A, Hirai H, Machii K, Ochiai M, Ohshima H, Tohma M, Kuwako K, Yamaguchi T, Toide H, Tohda E
Third Department of Internal Medicine, Toho University School of Medicine, Tokyo.
J Cardiol. 1988 Sep;18(3):731-8.
To assess the incidence of tricuspid regurgitation (TR) in mitral valve prolapse (MVP), 96 patients with MVP and 23 normal control subjects were studied. Subjects in the MVP group were further classified as a group with mitral regurgitation (MR(+) group: 61 cases), and MR(-) group (35 cases). The presence of TR in each group was studied by two-dimensional color flow mapping using a Toshiba SSH-65A apparatus. The incidence of TR was 49% in the MR(+) group and 34% in the MR(-) group, and both (35 cases). The presence of TR in each group was studied by two-dimensional color flow mapping using a Toshiba SSH-65A apparatus. The incidence of TR was 49% in the MR(+) group and 34% in the MR(-) group, and both values were statistically greater than 9% in the control group (p less than 0.001 and p less than 0.05, respectively). A female preponderance was observed only in the MR(+) group. Tricuspid valve prolapse was observed in six cases (10%) in the MR(+) group, two cases (6%) in the MR(-) group, and none in the control group. The mean tricuspid ring dimension did not differ significantly among the three groups. The female patients in MR(+) group had statistically greater measurements than the normal female subjects (p less than 0.01). In conclusion, the incidence of TR was statistically greater in female patients in the MR(+) group than in females in the other groups. It is suspected that functional or pathological changes which induce MVP are likely to progress to the tricuspid ring in female patients.
为评估二尖瓣脱垂（MVP）患者三尖瓣反流（TR）的发生率，我们对96例MVP患者和23名正常对照者进行了研究。MVP组患者进一步分为二尖瓣反流组（MR(+)组：61例）和无二尖瓣反流组（MR(-)组：35例）。使用东芝SSH - 65A设备通过二维彩色血流图研究每组中TR的存在情况。MR(+)组中TR的发生率为49%，MR(-)组为34%，两组发生率均显著高于对照组的9%（分别为p<0.001和p<0.05）。仅在MR(+)组中观察到女性占优势。MR(+)组中有6例（10%）观察到三尖瓣脱垂，MR(-)组中有2例（6%），对照组中未观察到。三组之间三尖瓣环尺寸的平均值无显著差异。MR(+)组中的女性患者测量值在统计学上高于正常女性受试者（p<0.01）。总之，MR(+)组中的女性患者TR发生率在统计学上高于其他组中的女性。怀疑诱发MVP的功能或病理变化在女性患者中可能会发展至三尖瓣环。
