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犬猫开颅手术的评估

Evaluation of craniotomy in dogs and cats.

作者信息

Niebauer G W, Dayrell-Hart B L, Speciale J

机构信息

Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104-6010.

出版信息

J Am Vet Med Assoc. 1991 Jan 1;198(1):89-95.

PMID:1995585
Abstract

Over a reporting period of 5 years, craniotomy was performed in 26 dogs and 5 cats with various intracranial lesions. X-ray computed tomography was performed in all animals prior to surgery. Twenty dogs and all cats had intracranial neoplasms; of these, 14 were meningioma, and 11 represented a wide variety of brain tumors and skeletal tumors. Three dogs were treated surgically for traumatic, open-skull fractures with cerebral damage, and 3 underwent biopsy to evaluate chronic inflammatory brain disease. The overall medium survival time was 212 days, the 1-year survival rate was 39%, and the 2-year survival rate was 20%. Dogs and cats with meningioma survived a mean 198 and 485 days, respectively, with 1-year survival rates of 30% for dogs and 50% for cats. The overall median survival time for animals with tumors other than meningeal intracranial neoplasms was 414 days, with a 1-year survival rate of 40%. The death of 19% of all animals could be related to the combination of advanced brain disease and surgery. Because fatality seldom occurred as a direct result of surgery, morbidity and mortality associated with craniotomy in pet animals can be seen as acceptably low. In 29 of 34 craniotomies, dura mater defects were left unsutured and no adverse effects were seen.

摘要

在为期5年的报告期内,对26只犬和5只猫进行了开颅手术,这些动物患有各种颅内病变。所有动物在手术前均进行了X线计算机断层扫描。20只犬和所有猫患有颅内肿瘤;其中,14只为脑膜瘤,11只代表多种脑肿瘤和骨肿瘤。3只犬因创伤性开放性颅骨骨折伴脑损伤接受了手术治疗,3只接受了活检以评估慢性炎症性脑病。总体中位生存时间为212天,1年生存率为39%,2年生存率为20%。患有脑膜瘤的犬和猫的平均生存时间分别为198天和485天,犬的1年生存率为30%,猫为50%。患有非脑膜颅内肿瘤的动物的总体中位生存时间为414天,1年生存率为40%。所有动物中有19%的死亡可能与晚期脑部疾病和手术的联合作用有关。由于很少因手术直接导致死亡,宠物开颅手术相关的发病率和死亡率可被视为低到可接受的程度。在34例开颅手术中的29例中,硬脑膜缺损未缝合,未观察到不良反应。

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