Curlewis J D, McLeod B J, Loudon A S
M.R.C./A.F.R.C. Comparative Physiology Research Group, Institute of Zoology, London, UK.
J Reprod Fertil. 1991 Jan;91(1):131-8. doi: 10.1530/jrf.0.0910131.
The pattern of LH secretion and response to exogenous GnRH was determined on 5 occasions during seasonal anoestrus of the Père David's deer hind. LH pulse frequency was low (3.3 +/- 0.6 pulses/18 h) in early anoestrus (February), increased significantly in mid-anoestrus (April; 8.4 +/- 1.4 pulses/18 h) and thereafter declined slightly in late anoestrus (June; 6.3 +/- 0.25 pulses/18 h). Mean LH concentrations also showed significant changes during anoestrus with higher levels in mid-anoestrus (April; 0.85 +/- 0.12 ng/ml) when compared with other times (0.53 +/- 0.05, 0.60 +/- 0.10, 0.68 +/- 0.06 and 0.71 +/- 0.05 ng/ml for February, March, May and June, respectively). LH pulse amplitude showed no significant changes during the study. The LH response to intravenous injections of 2 micrograms GnRH was lowest in early anoestrus (February), increased significantly in mid-anoestrus (April) and remained high through late anoestrus. The response during the luteal phase was similar to that seen during late anoestrus. These results indicate that seasonal anoestrus in the Père David's deer hind is not a uniform state but is characterized by an early period of 'deep' anoestrus.
在麋鹿母鹿季节性乏情期间，分5次测定了促黄体生成素（LH）的分泌模式及对外源性促性腺激素释放激素（GnRH）的反应。在乏情早期（2月），LH脉冲频率较低（3.3±0.6次脉冲/18小时），在乏情中期（4月）显著增加（8.4±1.4次脉冲/18小时），此后在乏情后期（6月）略有下降（6.3±0.25次脉冲/18小时）。平均LH浓度在乏情期间也有显著变化，与其他时间相比，乏情中期（4月）浓度更高（0.85±0.12纳克/毫升）（2月、3月、5月和6月分别为0.53±0.05、0.60±0.10、0.68±0.06和0.71±0.05纳克/毫升）。在研究期间，LH脉冲幅度没有显著变化。静脉注射2微克GnRH后，LH反应在乏情早期（2月）最低，在乏情中期（4月）显著增加，并在乏情后期一直保持较高水平。黄体期的反应与乏情后期相似。这些结果表明，麋鹿母鹿的季节性乏情并非一种均匀状态，而是以早期的“深度”乏情为特征。
