Department of Dermatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
J Dermatol. 2009 Dec;36(12):643-5. doi: 10.1111/j.1346-8138.2009.00723.x.
Autoimmune progesterone dermatitis is a rare disorder that presents as a cyclical cutaneous eruption during the luteal phase of the menstrual cycle. It typically occurs in women due to an autoimmune phenomenon to endogenous progesterone production. We describe a 34-year-old woman with an erythematous round plaque with blistering, which recurred a few days before her menstrual cycle, at the identical site on the left arm. The diagnosis of autoimmune progesterone dermatitis is made with i.d. skin testing on the affected lesion with progesterone. After the beginning of oral prednisolone (40 mg daily) therapy during menstruation, although slight recurrence appeared, the severity was significantly improved.
自身免疫性孕激素性皮炎是一种罕见的疾病，表现为月经周期黄体期的周期性皮肤发作。它通常发生在女性身上，是由于自身免疫现象对内源性孕激素产生。我们描述了一位 34 岁的女性，她的左手臂上出现了一个红斑性圆形斑块，伴有水疱，在月经周期前几天反复发作。自身免疫性孕激素性皮炎的诊断是通过在受影响的病变部位进行孕激素的 ID 皮肤试验。在月经期间开始口服泼尼松龙（每天 40 毫克）治疗后，尽管出现轻微复发，但严重程度显著改善。
