Department of Otolaryngology, University of Ottawa, Ottawa, Ontario.
J Otolaryngol Head Neck Surg. 2009 Dec;38(6):628-31.
The objective of this study was to significantly reduce the donor site morbidity associated with use of the radial forearm free flap (RFFF).
A pilot study to test the feasibility of topical tissue expanders to close the RFFF donor site.
The setting was a tertiary care teaching hospital.
This pilot study consisted of a series of 21 cases that used topical tissue expanders to preoperatively expand the forearm skin. This allowed primary closure of the donor site and, in some cases, closure with a full-thickness skin graft.
The main outcome measure was the ability to close the RFFF donor site without the use of a partial-thickness skin graft from the lateral thigh. Secondary outcome measures were the postoperative appearance of the donor site wound and function of the forearm.
Twenty-one cases were treated with the preoperative tissue expanders. It was possible to close the donor site without a partial-thickness skin graft from the thigh in 17 of these patients (81%). None of these patients experienced prolonged functional disability or serious complications.
The use of preoperative topical tissue expanders has the potential to significantly improve donor site morbidity in the RFFF.
本研究旨在显著降低游离桡侧前臂皮瓣（RFFF）应用相关的供区并发症。
一项测试应用局部组织扩张器闭合 RFFF 供区的可行性的试点研究。
该研究在一家三级护理教学医院进行。
这项试点研究共纳入 21 例患者，他们术前应用局部组织扩张器来扩张前臂皮肤。这使得供区能够一期闭合，在某些情况下，还可以使用全厚皮片闭合。
主要观察指标是无需取自大腿外侧的中厚皮片而闭合 RFFF 供区的能力。次要观察指标是供区伤口的术后外观和前臂功能。
21 例患者接受了术前组织扩张器治疗。在其中 17 例患者（81%）中，可以无需取自大腿的中厚皮片而闭合供区。这些患者均未发生长时间的功能障碍或严重并发症。
术前应用局部组织扩张器有潜力显著降低游离桡侧前臂皮瓣的供区并发症。
