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现场分诊可减少经皮冠状动脉介入治疗的急性 ST 段抬高型心肌梗死患者的治疗延迟,并改善其长期临床结局。

Field triage reduces treatment delay and improves long-term clinical outcome in patients with acute ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention.

机构信息

Department of Cardiology P, Gentofte University Hospital, Copenhagen, Denmark.

出版信息

J Am Coll Cardiol. 2009 Dec 8;54(24):2296-302. doi: 10.1016/j.jacc.2009.06.056.

DOI:10.1016/j.jacc.2009.06.056
PMID:19958965
Abstract

OBJECTIVES

We evaluated the independent impact of field triage on treatment delay and long-term clinical outcome in a large contemporary, consecutive population of ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (pPCI).

BACKGROUND

Reduction of treatment delay is crucial for patients with STEMI.

METHODS

From January 2005 to July 2008, 1,437 STEMI patients were treated with pPCI at a single high-volume invasive center. We present the 1-year outcome in this observational registry study.

RESULTS

A total of 616 patients were admitted by field triage and 821 by emergency departments. Baseline and angiographic variables were similar in the 2 populations. Patients admitted by field triage had a significantly shorter median door-to-balloon time compared with patients admitted by emergency department triage (83 min, interquartile range 67 to 100 min vs. 103 min, interquartile range 80 to 135 min; p<0.001). Door-to-balloon times of less than the recommended 90 min were achieved in 61% of field triage patients, but only in 36% of nonfield-triage patients (p<0.001). After adjustment for relevant baseline variables, patients admitted by field triage had a reduced risk of reaching the combined end point of all-cause mortality or nonfatal myocardial infarction (hazard ratio: 0.67; 95% confidence interval: 0.46 to 0.97; p=0.035).

CONCLUSIONS

This study shows that field triage of STEMI patients to pPCI significantly reduces treatment delay and improves outcome. These results emphasize the value of field triage as an important tool in the quest to improve clinical outcomes in STEMI patients undergoing pPCI.

摘要

目的

我们评估了现场分诊对接受直接经皮冠状动脉介入治疗(pPCI)的大样本连续 ST 段抬高型心肌梗死(STEMI)患者治疗延迟和长期临床结局的独立影响。

背景

缩短治疗延迟对 STEMI 患者至关重要。

方法

2005 年 1 月至 2008 年 7 月,在一家单中心高容量介入中心,1437 例 STEMI 患者接受了 pPCI 治疗。本研究为观察性注册研究,报告了患者 1 年的结局。

结果

共有 616 例患者由现场分诊收治,821 例患者由急诊收治。两组患者的基线和血管造影变量相似。与急诊分诊收治的患者相比,由现场分诊收治的患者门球时间明显更短(83 min,四分位距 67 至 100 min 与 103 min,四分位距 80 至 135 min;p<0.001)。现场分诊患者中,61%的患者门球时间小于推荐的 90 min,而非现场分诊患者中,只有 36%的患者门球时间小于 90 min(p<0.001)。校正相关基线变量后,由现场分诊收治的患者达到全因死亡率或非致死性心肌梗死联合终点的风险降低(风险比:0.67;95%置信区间:0.46 至 0.97;p=0.035)。

结论

本研究表明,对 STEMI 患者进行现场分诊至 pPCI 可显著缩短治疗延迟,改善结局。这些结果强调了现场分诊作为一种重要工具的价值,有助于改善接受 pPCI 的 STEMI 患者的临床结局。

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