Dowers Kristy L, Hawley Jennifer R, Brewer Melissa M, Morris Arianne K, Radecki Steven V, Lappin Michael R
Department of Clinical Sciences, Colorado State University, Fort Collins, CO, USA.
J Feline Med Surg. 2010 Apr;12(4):314-21. doi: 10.1016/j.jfms.2009.10.007. Epub 2009 Dec 2.
Feline gingivostomatitis (FGS) is a common syndrome in cats; feline calicivirus (FCV), feline herpesvirus 1 (FHV-1), and Bartonella species are common differential diagnoses. In this study, blood from 70 cats with FGS and 61 healthy control cats was tested for Bartonella species antibodies in serum by enzyme-linked immunosorbent assay and Western blot immunoassay and DNA in blood using a conventional polymerase chain reaction assay. Additionally, fresh oral biopsies from cats with FGS (n=42) and 19 healthy controls were tested for FCV RNA, FHV-1 DNA and Bartonella species DNA. The prevalence rates for Bartonella species antibodies and DNA in the blood and the tissues did not differ between the two groups. FHV-1 DNA was also not significantly different between groups. Only FCV RNA was present in significantly more cats with FGS (40.5%) than control cats (0%). The results suggest that FCV was associated with FGS in some of the cats.
猫口腔炎（FGS）是猫常见的综合征；猫杯状病毒（FCV）、猫疱疹病毒1型（FHV-1）和巴尔通体属是常见的鉴别诊断对象。在本研究中，通过酶联免疫吸附测定和蛋白质印迹免疫测定检测了70只患有FGS的猫和61只健康对照猫血清中的巴尔通体属抗体，并使用传统聚合酶链反应测定检测了血液中的DNA。此外，对42只患有FGS的猫和19只健康对照猫的新鲜口腔活检组织进行了FCV RNA、FHV-1 DNA和巴尔通体属DNA检测。两组之间血液和组织中巴尔通体属抗体和DNA的患病率没有差异。两组之间FHV-1 DNA也没有显著差异。只有FCV RNA在患有FGS的猫（40.5%）中比对照猫（0%）中显著更多。结果表明，FCV在一些猫中与FGS有关。
