Department of Radiology, Wake Forest University School of Medicine, Medical Center Blvd, Winston-Salem, NC 27157, USA.
Radiographics. 2009 Oct;29(6):1827-46. doi: 10.1148/rg.296095510.
Crohn disease is a complex pathologic process with an unpredictable lifelong course that includes frequent relapses. It often affects young patients, who are most vulnerable to the potential adverse effects of repeated exposure to ionizing radiation from computed tomography performed for diagnosis and surgical planning. The small intestine is the bowel segment that is most frequently affected, but it is the least accessible with endoscopic techniques. Magnetic resonance (MR) enterography has the potential to safely and noninvasively meet the imaging needs of patients with Crohn disease without exposing them to ionizing radiation. Appropriate use of MR enterography requires a carefully crafted protocol to depict signs of active inflammation as well as complications such as bowel obstruction, fistulas, and abscesses. Interpretation of MR enterographic images requires familiarity with the imaging signs and mimics of active bowel inflammation and stenosis. Although MR enterography currently is helpful for management in individual patients, the standardization of acquisition protocols and interpretive methods would increase its usefulness for more rigorous, systematic assessments of Crohn disease treatment regimens.
克罗恩病是一种复杂的病理过程，具有不可预测的终身病程，包括频繁复发。它通常影响年轻患者，他们最容易受到因诊断和手术计划而进行的计算机断层扫描所带来的反复电离辐射的潜在不良影响。小肠是最常受影响的肠道部位，但它是通过内镜技术最难以接近的部位。磁共振（MR）肠造影术有可能安全、无创地满足克罗恩病患者的成像需求，而不会使他们暴露于电离辐射之下。适当使用 MR 肠造影术需要精心制定方案来描绘活动炎症的迹象以及肠梗阻、瘘管和脓肿等并发症。解读 MR 肠造影图像需要熟悉活动性肠炎和狭窄的影像学征象和模拟。尽管 MR 肠造影术目前有助于对个别患者的治疗管理，但获取协议和解释方法的标准化将增加其对更严格、系统评估克罗恩病治疗方案的有用性。
