Mantarro Annalisa, Scalise Paola, Guidi Elisa, Neri Emanuele
Annalisa Mantarro, Paola Scalise, Elisa Guidi, Emanuele Neri, Department of Translational Research and New Techno-logies in Medicine and Surgery, Diagnostic Radiology, 56126 Pisa, Italy.
World J Radiol. 2017 Feb 28;9(2):46-54. doi: 10.4329/wjr.v9.i2.46.
Crohn's disease (CD) is a chronic inflammatory disease of the gastrointestinal tract, with unpredictable clinical course by phases of relapses alternating with other of quiescence. The etiology is multifactorial and is still not completely known; globally the westernization of lifestyle is causing an increasing incidence of CD, with peak age of 20-30 years. The diagnostic workup begins with the evaluation of the clinical history, physical examination and laboratory tests. However, the clinical assessment is subjected interobserver variability and, occasionally, the symptoms of acute and chronic inflammation may be indistinguishable. In this regards, the role of magnetic resonance (MR) enterography is crucial to determine the extension, the disease activity and the presence of any complications without ionizing radiations, making this method very suitable for young population affected by CD. The purpose of this review article is to illustrate the MR enterography technique and the most relevant imaging findings of CD, allowing the detection of small bowel involvement and the assessment of disease activity.
克罗恩病(CD)是一种胃肠道慢性炎症性疾病,其临床病程不可预测,表现为复发期与静止期交替。病因是多因素的,目前仍不完全清楚;在全球范围内,生活方式的西化导致CD的发病率不断上升,发病高峰年龄为20 - 30岁。诊断检查始于对临床病史、体格检查和实验室检查的评估。然而,临床评估存在观察者间差异,而且急性和慢性炎症的症状有时可能难以区分。在这方面,磁共振(MR)小肠造影的作用至关重要,它可以在不使用电离辐射的情况下确定病变范围、疾病活动度以及是否存在任何并发症,这使得该方法非常适合受CD影响的年轻人群。这篇综述文章的目的是阐述MR小肠造影技术以及CD最相关的影像学表现,以便能够检测小肠受累情况并评估疾病活动度。