[Simulation study of anti-hypoxia active fraction of Xiangdan injection by support vector machine].

OBJECTIVE

To investigate the anti-hypoxia active fraction of Xiangdan injection.

METHODS

The anti-hypoxia experiment under normal pressure with mice was adopted on the basis of orthogonal design, and a support vector machine model was established for pharmacodynamics prediction of TCM prescriptions. Moreover, the anti-hypoxia active fraction of Xiangdan injection was determined by experimental confirmation.

RESULTS

The prediction model established in this study could predict the drug actions of different formulas.

CONCLUSION

As indicated in model prediction and experimental confirmation, the pharmacodynamic actions of several formulas are superior to that of the original formula, and ADE has the best effect.