Departamento de Microbiología, Facultad de Medicina, Universidad Autónoma de Nuevo León, Mexico.
Epidemiol Infect. 2010 May;138(5):645-54. doi: 10.1017/S0950268809991361. Epub 2009 Dec 7.
Coagulase-negative staphylococci (CNS) are increasingly recognized to cause clinically significant infections, with S. epidermidis often cited as the third most common cause of nosocomial sepsis. Among CNS, there is a high prevalence of methicillin resistance associated with staphylococcal cassette chromosome (SCCmec) elements. Although identical SCCmec types can exist in S. aureus and CNS, some novel classes of SCCmec may be unique to CNS. Differences in the accuracy of identification of CNS species and use of non-standardized methods for the detection of methicillin resistance have led to confusing data in the literature. In addition to the review of SCCmec in CNS, in this paper we report a 2-year surveillance of methicillin-resistant CNS in a tertiary-care hospital in Guadalajara, Mexico.
凝固酶阴性葡萄球菌（CNS）越来越被认为会引起具有临床意义的感染，表皮葡萄球菌常被认为是医院获得性败血症的第三大常见原因。在 CNS 中，与葡萄球菌盒式染色体（SCCmec）元件相关的耐甲氧西林现象非常普遍。尽管相同的 SCCmec 类型可能存在于金黄色葡萄球菌和 CNS 中，但某些新型 SCCmec 可能是 CNS 所特有的。由于 CNS 物种鉴定的准确性差异以及耐甲氧西林检测方法不标准化，导致文献中的数据混乱。除了 CNS 中 SCCmec 的综述外，本文还报告了在墨西哥瓜达拉哈拉的一家三级保健医院对耐甲氧西林 CNS 进行的为期 2 年的监测。
