猪繁殖与呼吸综合征病毒疫苗株和流行株中的重组。
Recombination in vaccine and circulating strains of porcine reproductive and respiratory syndrome viruses.
机构信息
Huazhong Agricultural University, Wuhan 430070, People's Republic of China.
出版信息
Emerg Infect Dis. 2009 Dec;15(12):2032-5. doi: 10.3201/eid1512.090390.
Abstract
Em2007, a porcine reproductive and respiratory syndrome virus (PRRSV) variant with a unique 68 aa deletion in Nsp2, was recently isolated in China. Phylogenetic and molecular evolutionary analyses indicated that Em2007 is a natural recombinant between a vaccine strain of PRRSV and circulating virus. We also tested its pathogenicity in piglets.
摘要
2007 年，在中国分离到一株具有独特 Nsp2 基因 68 个氨基酸缺失的猪繁殖与呼吸综合征病毒（PRRSV）变异株。遗传进化分析表明，该变异株是 PRRSV 疫苗株与流行毒株之间发生自然重组的结果。我们还在仔猪上对其致病性进行了检测。
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