人精浆中碳水化合物抗原15-3和黏液性碳水化合物抗原免疫反应性

Carbohydrate antigen 15-3 and mucinous carbohydrate antigen immunoreactivities in human seminal plasma.

作者信息

González Buitrago J M, Cava F, Moyano J C, Navajo J A

机构信息

Servicio de Análisis Clínicos, Hospital Virgen de la Vega, Salamanca, Spain.

出版信息

Tumour Biol. 1991;12(1):24-7. doi: 10.1159/000217684.

DOI:10.1159/000217684

PMID:1996402

Abstract

Carbohydrate antigen 15-3 (CA 15-3) and mucinous carbohydrate antigen (MCA) immunoreactivities were detected in human seminal plasma. Mean values for CA 15-3 (8.2 +/- 3.7 U/ml, range 2.6 - 18.4 U/ml) and MCA (13.8 +/- 8.2 U/ml, range 2.1-31.9 U/ml) in the seminal plasma were of the same magnitude as that found in serum. No correlation was obtained between seminal plasma, either CA 15-3 or MCA immunoreactivities, and volume of seminal plasma, sperm count or percent of motile spermatozoa. Seminal plasma CA 15-3 and MCA levels were significantly (p less than 0.001) correlated (r = 0.55). The nature and origin of CA 15-3 and MCA immunoreactivities in human plasma are unknown.

摘要

在人类精浆中检测到碳水化合物抗原15-3（CA 15-3）和黏液性碳水化合物抗原（MCA）免疫反应性。精浆中CA 15-3的平均值为（8.2±3.7 U/ml，范围2.6 - 18.4 U/ml），MCA的平均值为（13.8±8.2 U/ml，范围2.1 - 31.9 U/ml），与血清中的水平相当。精浆中CA 15-3或MCA免疫反应性与精浆体积、精子计数或活动精子百分比之间均未发现相关性。精浆中CA 15-3和MCA水平显著相关（p<0.001）（r = 0.55）。人类血浆中CA 15-3和MCA免疫反应性的性质和来源尚不清楚。