增强高流量和低流量脉管系统激光散斑成像的方法。
Methods to enhance laser speckle imaging of high-flow and low-flow vasculature.
作者信息
Choi Bernard, Ringold Tyson L, Kim Jeehyun
机构信息
Department of Biomedical Engineering, Beckman Laser Institute, University of California, Irvine, CA 92612, USA.
出版信息
Annu Int Conf IEEE Eng Med Biol Soc. 2009;2009:4073-6. doi: 10.1109/IEMBS.2009.5333204.
Abstract
The objective of this paper is to present two methods to extend the response range of laser speckle imaging (LSI). We report on the use of two methods (image exposure time control and magnetomotive actuation of exogenous contrast agents) to enhance characterization of high- and low-flow vasculature, respectively. With an exposure time of 10 and 0.01 ms, the linear response range extended to 10 and 280 mm/s, respectively. With application of an AC magnetic field to a solution of stagnant SPIO particles, an apparent increase of approximately 3x in speckle flow index was induced.
摘要
本文的目的是介绍两种扩展激光散斑成像（LSI）响应范围的方法。我们报告了两种方法（图像曝光时间控制和外源性造影剂的磁驱动）分别用于增强对高流量和低流量血管系统的表征。曝光时间为10毫秒和0.01毫秒时，线性响应范围分别扩展到10毫米/秒和280毫米/秒。对停滞的超顺磁性氧化铁（SPIO）颗粒溶液施加交流磁场时，散斑流动指数明显增加了约3倍。
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