宾夕法尼亚大学利用漫射光学层析成像与光谱技术进行乳腺癌特征分析及治疗监测

Diffuse optical tomography & spectroscopy in breast cancer characterization & therapy monitoring at UPENN.

作者信息

Choe Regine

机构信息

Department of Physics & Astronomy, University of Pennsylvania, Philadelphia, PA 19104, USA.

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2009;2009:6335-7. doi: 10.1109/IEMBS.2009.5333164.

DOI:10.1109/IEMBS.2009.5333164

PMID:19964156

Abstract

In this paper, I will provide a broad review of breast cancer research conducted at the University of Pennsylvania and collaborative work with other institution. Our group led by Dr. Arjun G. Yodh has been actively exploring functional and physiological information available via the diffuse optical technique and investigate its use in the area of in vivo breast cancer detection, diagnosis, and therapy monitoring. In particular, the recent advances in malignant and benign lesion differentiation from 3D diffuse optical tomography, 3D fluorescence diffuse optical tomography using Indocyanine Green injection, and neoadjuvant chemotherapy monitoring with diffuse correlation spectroscopy will be presented.

摘要

在本文中，我将对宾夕法尼亚大学开展的乳腺癌研究以及与其他机构的合作工作进行全面回顾。由阿尔君·G·约德博士领导的我们团队，一直在积极探索通过漫射光学技术可获取的功能和生理信息，并研究其在体内乳腺癌检测、诊断和治疗监测领域的应用。特别地，将介绍从三维漫射光学断层扫描、使用吲哚菁绿注射的三维荧光漫射光学断层扫描进行恶性和良性病变鉴别方面的最新进展，以及利用漫射相关光谱法进行新辅助化疗监测的情况。