用于小动物研究的可植入微机电系统药物输送泵。

Implantable MEMS drug delivery pumps for small animal research.

作者信息

Meng Ellis, Li Po-Ying, Lo Ronalee, Sheybani Roya, Gutierrez Christian

机构信息

Departments of Biomedical and Electrical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA 90089-1111, USA. ellis.meng@ usc.edu

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2009;2009:6696-8. doi: 10.1109/IEMBS.2009.5333284.

DOI:10.1109/IEMBS.2009.5333284

PMID:19964178

Abstract

Advanced devices capable of selective delivery of compounds to targeted tissues are lacking, especially in small animal research. Biomedical microelectromechanical systems (bioMEMS) are uniquely suited to this application through the combination of scalability and precise control of fluid handling. Polymer-based drug delivery components and pumps for acute and chronic delivery in small animals are discussed.

摘要

目前缺乏能够将化合物选择性递送至目标组织的先进设备，尤其是在小动物研究中。生物医学微机电系统（bioMEMS）通过可扩展性和流体处理的精确控制相结合，特别适合于这一应用。本文讨论了用于小动物急性和慢性给药的基于聚合物的药物递送组件和泵。