MEMS：药物输送系统。

MEMS: Enabled Drug Delivery Systems.

机构信息

Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, 1042 Downey Way DRB-140, Los Angeles, CA, 90089-1111, USA.

Department of Electrical Engineering, Viterbi School of Engineering, University of Southern California, 3651 Watt Way VHE-602, Los Angeles, CA, 90089-0241, USA.

出版信息

Adv Healthc Mater. 2015 May;4(7):969-82. doi: 10.1002/adhm.201400772. Epub 2015 Feb 20.

DOI:10.1002/adhm.201400772

PMID:25703045

Abstract

Drug delivery systems play a crucial role in the treatment and management of medical conditions. Microelectromechanical systems (MEMS) technologies have allowed the development of advanced miniaturized devices for medical and biological applications. This Review presents the use of MEMS technologies to produce drug delivery devices detailing the delivery mechanisms, device formats employed, and various biomedical applications. The integration of dosing control systems, examples of commercially available microtechnology-enabled drug delivery devices, remaining challenges, and future outlook are also discussed.

摘要

药物输送系统在医疗条件的治疗和管理中起着至关重要的作用。微机电系统（MEMS）技术允许开发用于医疗和生物应用的先进微型设备。本综述介绍了使用 MEMS 技术生产药物输送装置，详细介绍了输送机制、所采用的装置形式以及各种生物医学应用。还讨论了剂量控制系统的集成、商业上可用的微技术药物输送装置的示例、存在的挑战和未来展望。