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神经刺激电流波形的优化设计

Optimal design of neural stimulation current waveforms.

作者信息

Halpern Mark

机构信息

National Information and Communication Technologies Australia (NICTA) Victoria Research Laboratory (VRL), Department of Electrical and Electronic Engineering, University of Melbourne, Parkville, Victoria 3010, Australia.

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2009;2009:189-92. doi: 10.1109/IEMBS.2009.5333567.

Abstract

This paper contains results on the design of electrical signals for delivering charge through electrodes to achieve neural stimulation. A generalization of the usual constant current stimulation phase to a stepped current waveform is presented. The electrode current design is then formulated as the calculation of the current step sizes to minimize the peak electrode voltage while delivering a specified charge in a given number of time steps. This design problem can be formulated as a finite linear program, or alternatively by using techniques for discrete-time linear system design.

摘要

本文包含了关于设计电信号以通过电极输送电荷来实现神经刺激的研究结果。文中提出了将通常的恒流刺激阶段推广为阶梯电流波形的方法。然后将电极电流设计表述为计算电流步长,以便在给定数量的时间步内输送指定电荷的同时使电极峰值电压最小化。这个设计问题可以被表述为一个有限线性规划问题,或者也可以通过使用离散时间线性系统设计技术来解决。

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