在CT结肠造影中使用三维表面的水平集对息肉进行线性测量。
Linear measurement of polyps in CT colonography using level sets on 3D surfaces.
作者信息
Tan Sovira, Yao Jianhua, Ward Michael M, Summers Ronald M
机构信息
National Institute of Arthritis and Musculoskeletal and Skin diseases, National Institutes of Health, Clinical Center, 10 Center Drive MSC 1182, Bethesda, MD 20892, USA.
出版信息
Annu Int Conf IEEE Eng Med Biol Soc. 2009;2009:3617-20. doi: 10.1109/IEMBS.2009.5334027.
CT colonography has emerged as a minimally invasive alternative to optical colonoscopy for the screening of polyps which are the precursors to colon cancer. Accurate polyp measurement is crucial as the size of a polyp is considered an indication of its potential for malignancy. We present a novel method for the automatic measurement of polyps. It is based on a level set algorithm capable of evolving on the surface of a 3D object represented by a triangular mesh. It is guided by curvature features and is capable of segmenting the polyp neck, that is, the ridgeline/crestline formed around the polyp by its merging to the colon wall. Our method was validated on 40 polyp surfaces obtained from real clinical data. A 3D manual measurement was used as the reference standard. A correlation of 0.825 was found between polyp measurements from our new method and the reference standard.
计算机断层结肠成像已成为一种微创替代方法，用于替代光学结肠镜检查来筛查息肉，而息肉是结肠癌的前身。准确测量息肉至关重要，因为息肉大小被视为其恶性潜能的一个指标。我们提出了一种自动测量息肉的新方法。它基于一种水平集算法，该算法能够在由三角网格表示的三维物体表面上演变。它由曲率特征引导，并且能够分割息肉颈部，即息肉与结肠壁融合形成的脊线/嵴线。我们的方法在从真实临床数据中获取的40个息肉表面上得到了验证。使用三维手动测量作为参考标准。我们的新方法与参考标准之间的息肉测量结果相关性为0.825。
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