Sadleir R J, Tang Te, Tucker Aaron S, Borum Peggy, Weiss Michael
Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611-6131, USA.
Annu Int Conf IEEE Eng Med Biol Soc. 2009;2009:3169-72. doi: 10.1109/IEMBS.2009.5334510.
We have developed a sensitive EIT protocol for detection of intraventricular bleeding. A common model of human neonates is the neonatal piglet. We used our method to test the sensitivity of our method and device to small amounts of blood-like fluid injected near the left and right ventricles of a piglet cadaver. Comparing blood-like fluid detection in open an closed piglet skulls, we found that we could detect amounts of blood less than 0.5 ml, which is smaller than that required for our target of detecting grade II intraventricular hemorrhages in human neonates.
我们开发了一种用于检测脑室内出血的灵敏电阻抗断层成像(EIT)协议。人类新生儿的常见模型是新生仔猪。我们使用我们的方法来测试我们的方法和设备对在仔猪尸体左、右心室附近注入少量类血液液体的敏感性。通过比较开放和封闭仔猪颅骨中的类血液液体检测情况,我们发现我们能够检测到少于0.5毫升的血液量,这比我们检测人类新生儿II级脑室内出血目标所需的量要小。