Sharma Vikrant, Kashyap Dheerendra, Mathker Aditya, Narvenkar Sweta, Bensalah Karim, Kabbani Wareef, Tuncel Altug, Cadeddu Jeffrey A, Liu Hanli
International Techlink Group, Inc, Arlington, TX 76010, USA.
Annu Int Conf IEEE Eng Med Biol Soc. 2009;2009:118-21. doi: 10.1109/IEMBS.2009.5334830.
We present the method and application of optical reflectance spectroscopy to differentiate prostate cancer from normal tissue using a needle like, bifurcated, fiber-optic probe. An analytical expression to model light reflectance recently published by Zonios et. al. was used to derive optical properties of tissue. A total of 23 cases of human prostate specimens were investigated to analyze statistical differences between the respective cancerous tissues versus normal tissues. The results demonstrate that the derived hemodynamic parameters and optical properties can serve as good bio-markers to differentiate tumor tissue from normal tissue in human prostate.
我们展示了使用针状、分叉光纤探头的光学反射光谱法来区分前列腺癌与正常组织的方法及应用。Zonios等人最近发表的用于模拟光反射的解析表达式被用来推导组织的光学特性。共对23例人类前列腺标本进行研究，以分析各癌组织与正常组织之间的统计学差异。结果表明，所推导的血液动力学参数和光学特性可作为良好的生物标志物，用于区分人类前列腺中的肿瘤组织与正常组织。
