Klanecky Alicia K, McChargue Dennis E
Department of Psychology, University of Nebraska-Lincoln, Lincoln, NE, USA.
Ment Health Subst Use. 2009 Oct 1;2(3):191-202. doi: 10.1080/17523280903192011.
Research has reported a high rate of substance dependence in traumatized individuals who do not develop PTSD (TWP). While past studies have failed to consistently demonstrate that TWP individuals experience PTSD symptoms, findings have indicated that TWP and a history of substance dependence aside from nicotine dependence (SDH) are linked to affect disruption. AIMS: The present study explored positive and negative affective mechanisms across four groups with varying SDH and TWP including TWP + SDH, TWP only, SDH only, or no history. Researchers hypothesized that adults (n = 78) would be more emotionally reactive to an experimentally-induced negative mood compared to a neutral mood induction as the presence of co-existing TWP and SDH increased. METHOD: After a brief telephone screening, eligible participants completed baseline self-report questionnaires and experimentally-manipulated negative and neutral mood inductions. RESULTS: Most notably, results showed a significant TWP x SDH x Mood induction interaction (F (1, 63) = 4.154; Mse = 51.999; p = .046) for positive affect responses. Simple effects indicated that all participants except TWP + SDH individuals experienced a significant decrease in positive affect during the negative compared to the neutral mood condition. CONCLUSION: Findings may identify a protective mechanism for relapse among individuals with a history of both TWP and SDH.
研究报告称,未患创伤后应激障碍(TWP)的受创伤个体中物质依赖率很高。虽然过去的研究未能始终如一地证明TWP个体经历创伤后应激障碍症状,但研究结果表明,TWP以及除尼古丁依赖之外的物质依赖史(SDH)与情感紊乱有关。目的:本研究探讨了四组不同SDH和TWP情况(包括TWP + SDH、仅TWP、仅SDH或无病史)中的正负情感机制。研究人员假设,随着共存的TWP和SDH的增加,与中性情绪诱导相比,成年人(n = 78)在实验诱导的负面情绪下会更易产生情绪反应。方法:经过简短的电话筛选后,符合条件的参与者完成了基线自我报告问卷,并接受了实验操纵的负面和中性情绪诱导。结果:最值得注意的是,研究结果显示,在积极情感反应方面存在显著的TWP x SDH x情绪诱导交互作用(F (1, 63) = 4.154;均方误差 = 51.999;p = .046)。简单效应表明,与中性情绪条件相比,除TWP + SDH个体外,所有参与者在负面情绪期间的积极情感均显著下降。结论:研究结果可能揭示了TWP和SDH病史个体复发的一种保护机制。