Stoffels I, Wolter T P, Sailer A M, Pallua N
Klinik für Plastische Chirurgie, Hand- und Verbrennungschirurgie, Universitätsklinikum RWTH Aachen, Pauwelsstr. 30, 52074 Aachen.
Hautarzt. 2010 Apr;61(4):332-8. doi: 10.1007/s00105-009-1886-y.
For more than two decades silicone has successfully been employed in the treatment and prevention of hypertrophic scars and keloids as a painless noninvasive modality with few side effects. In the present trial, after 3 months of treatment the Patient Scar Assessment Scale demonstrated that patient satisfaction with the silicone application was significantly higher compared to placebo. When treatment was stopped after 3 months, the topical silicone spray did not exhibit any lasting long-term impact on the objective results of scar formation. Due to the significant differences in patient satisfaction once treatment has ended and since the administration is safe and simple, any final decision on treatment indication should be tailored to the patient and include the psychological well-being of the patient as well as the temporary improvement in scar formation during treatment.
二十多年来，硅胶已成功用于治疗和预防增生性瘢痕和瘢痕疙瘩，它是一种无痛、无创的治疗方式，副作用很少。在本次试验中，经过3个月的治疗，患者瘢痕评估量表显示，与安慰剂相比，患者对硅胶治疗的满意度显著更高。3个月后停止治疗时，外用硅胶喷雾对瘢痕形成的客观结果未表现出任何持久的长期影响。由于治疗结束后患者满意度存在显著差异，且给药安全简便，任何关于治疗适应症的最终决定都应根据患者情况量身定制，包括患者的心理健康以及治疗期间瘢痕形成的暂时改善情况。
