Schauber J
Klinik für Dermatologie und Allergologie, Ludwig-Maximilians Universität München, München, Deutschland.
Hautarzt. 2010 Jan;61(1):33-8. doi: 10.1007/s00105-009-1812-3.
Perianal eczema is a common diagnosis in patients seeking help from a proctologist/dermatologist. Due to their different etiology, perianal eczemas can be subdivided into irritant-toxic, atopic, and contact allergic forms. While these three entities may present with a similar clinical picture, the correct differential diagnosis is crucial for rapid successful therapy. After treatment of any underlying proctologic disease, low-potency corticosteroid or calcineurin inhibitor formulations may be applied for short-term topical perianal therapy. Preparations containing zinc oxide and cleaning of the perianal region with clear water can support the healing process. Patients should avoid topical irritants and potential contact allergens. Perianal eczema resistant to therapy should be further evaluated by histopathological workup to exclude precancerous or malignant skin disease.
肛周湿疹是寻求直肠科医生/皮肤科医生帮助的患者中的常见诊断。由于病因不同，肛周湿疹可细分为刺激性毒性、特应性和接触过敏性三种类型。虽然这三种类型可能呈现相似的临床表现，但正确的鉴别诊断对于快速成功治疗至关重要。在治疗任何潜在的直肠疾病后，可应用低效皮质类固醇或钙调神经磷酸酶抑制剂制剂进行短期肛周局部治疗。含氧化锌的制剂以及用清水清洁肛周区域有助于愈合过程。患者应避免局部刺激物和潜在的接触过敏原。对治疗有抵抗的肛周湿疹应通过组织病理学检查进一步评估，以排除癌前或恶性皮肤病。
