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II型特发性黄斑毛细血管扩张症和软性融合性玻璃膜疣。

Type II idiopathic macular telangiectasia and soft confluent drusen.

作者信息

Querques Giuseppe, Coscas Gabriel, Soubrane Gisèle, Souied Eric H

机构信息

Department of Ophthalmology, University of Paris XII, Centre Hospitalier Intercommunal de Creteil, France.

出版信息

Eur J Ophthalmol. 2010 Mar-Apr;20(2):466-8. doi: 10.1177/112067211002000234.

Abstract

PURPOSE

To describe the simultaneous presentation of soft confluent drusen and type 2 idiopathic macular telangiectasia (IMT) in both eyes of one patient.

METHODS

A 79-year-old man with bilateral metamorphopsia and gradual reduction of central vision underwent a complete ophthalmologic examination.

RESULTS

In this patient, fundus biomicroscopy revealed soft confluent drusen and a cystic appearance within the fovea, and fluorescein angiography (FA) showed late dye leakage. Interestingly, indocyanine green angiography (ICGA) showed absence of late hypercyanescence, and spectral domain optical coherence tomography (Spectralis SD-OCT) clearly revealed the presence of bilateral foveal cysts with thinning and loss of the normal architecture of the outer retina, as well as absence of retinal thickening within the parafoveolar area showing discrete late dye leakage on FA. Based on these findings, the patient was diagnosed with nonexudative age-related macular degeneration with foveal soft confluent drusen, and coincident nonproliferative type 2 IMT.

CONCLUSIONS

To our knowledge, there is no previously reported case of simultaneous presentation of soft confluent drusen and type 2 IMT. This report highlights the importance of ICGA and OCT in the correct diagnosis of such cases.

摘要

目的

描述1例患者双眼同时出现软性融合性玻璃膜疣和2型特发性黄斑毛细血管扩张症(IMT)的情况。

方法

一名79岁男性,双眼出现视物变形及中心视力逐渐下降,接受了全面的眼科检查。

结果

该患者眼底生物显微镜检查发现软性融合性玻璃膜疣及黄斑区呈囊样外观,荧光素血管造影(FA)显示晚期染料渗漏。有趣的是,吲哚菁绿血管造影(ICGA)显示无晚期高荧光,光谱域光学相干断层扫描(Spectralis SD-OCT)清楚地显示双眼黄斑囊肿的存在,伴有外层视网膜正常结构变薄和缺失,且黄斑旁区域无视网膜增厚,FA显示该区域有离散性晚期染料渗漏。基于这些发现,该患者被诊断为伴有黄斑软性融合性玻璃膜疣的非渗出性年龄相关性黄斑变性,以及并存的非增殖性2型IMT。

结论

据我们所知,此前尚无软性融合性玻璃膜疣和2型IMT同时出现的病例报道。本报告强调了ICGA和OCT在正确诊断此类病例中的重要性。

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