Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria.
Onderstepoort J Vet Res. 2009 Mar;76(1):91-5.
African swine fever (ASF) is a devastating haemorrhagic fever of pigs that causes up to 100% mortality, for which there is no vaccine. It is caused by a unique DNA virus that is maintained in an ancient cycle between warthogs and argasid ticks, making it the only known DNA arbovirus. ASF has a high potential for transboundary spread, and has twice been transported from Africa to other continents--Europe and subsequently the Caribbean and Brazil (1957, 1959) and the Caucasus (2007). It is also a devastating constraint for pig production in Africa. Research at Onderstepoort Veterinary Institute has made and is making important contributions to knowledge of this disease, focusing on the cycle in warthogs and tampans and transmission from that cycle to domestic pigs, resistance to its effects in domestic pigs, and the molecular genetic characterisation and epidemiology of the virus.
非洲猪瘟（ASF）是一种毁灭性的猪出血热，死亡率高达 100%，目前尚无疫苗。它是由一种独特的 DNA 病毒引起的，这种病毒在疣猪和革螨之间维持着一种古老的循环，使其成为唯一已知的 DNA 虫媒病毒。ASF 具有很强的跨境传播潜力，已经两次从非洲传播到其他大陆——欧洲，随后传播到加勒比海和巴西（1957 年、1959 年）和高加索地区（2007 年）。它也是非洲养猪业的毁灭性制约因素。Onderstepoort 兽医研究所的研究对这种疾病的认识做出了并正在做出重要贡献，重点研究疣猪和塔潘斯猪的循环以及从该循环向家猪的传播、家猪对其影响的抵抗力，以及病毒的分子遗传特征和流行病学。
