Guo Zhiyong, Cheng Fan, Zou Kun, Wang Junzhi, She Zhigang, Lin Yongcheng
Hubei Key Laboratory of Natural Products Research and Development (China Three Gorges University), Yichang, Hubei Province 443002, People's Republic of China.
Nat Prod Commun. 2009 Nov;4(11):1481-3.
A new metabolite, 7-hydroxyjanthinone (1), was isolated from the mangrove endophytic fungus Penicillium sp. (SBE-8), together with two known compounds, janthinone (2) and citrinin (3). The structures of these compounds were identified by spectroscopic methods. Compounds 1 and 2 showed no cytotoxicity against KB and KBv cell lines when tested by the MTT method, but compound 3 was weakly active.
从红树林内生真菌青霉属菌株（SBE - 8）中分离出一种新的代谢产物7 - 羟基紫金牛醌（1），同时还分离出两种已知化合物紫金牛醌（2）和桔霉素（3）。通过光谱方法鉴定了这些化合物的结构。采用MTT法检测时，化合物1和2对KB和KBv细胞系无细胞毒性，但化合物3具有微弱活性。
