尼泊尔特赖地区登革热病毒感染的血清学研究。

Serological study of dengue virus infection in Terai region, Nepal.

作者信息

Sah O P, Subedi S, Morita K, Inone S, Kurane I, Pandey B D

机构信息

Department of Microbiology, National College, Kathmandu, Nepal.

出版信息

Nepal Med Coll J. 2009 Jun;11(2):104-6.

PMID:19968149

Abstract

A cross-sectional study was conducted to determine dengue virus IgM-positive rate in Terai region, Nepal from August to December 2007. Serum samples were collected from 183 symptomatic cases. The samples were examined for dengue virus specific IgM using particle agglutination test. Of 183 serum samples, 55 (30.0%) had positive for dengue IgM antibody. The positive rate was highest (50.0%) in Biratnagar, and lowest (19.6%) in Chitwan male to female ratio was 2:1 in IgM-positive populations. IgM-positive rate was 29.0% at ages 21-30, 25.4% at ages 11-20 and 23.6% at ages 0-10, but 10.9% at ages 31-40, and ages over 40. There was not significant association between occupation of the patients and positive rate among farmer, labour, service, business and student.

摘要

2007年8月至12月在尼泊尔特莱地区开展了一项横断面研究，以确定登革病毒IgM阳性率。从183例有症状病例中采集血清样本。使用颗粒凝集试验检测样本中的登革病毒特异性IgM。在183份血清样本中，55份（30.0%）登革IgM抗体呈阳性。阳性率在比拉特纳格尔最高（50.0%），在奇特旺最低（19.6%）。IgM阳性人群中男女比例为2:1。21至30岁年龄组的IgM阳性率为29.0%，11至20岁年龄组为25.4%，0至10岁年龄组为23.6%，但31至40岁年龄组及40岁以上年龄组为10.9%。患者职业（农民、劳工、服务业人员、商人及学生）与阳性率之间无显著关联。