Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
J Sex Med. 2010 Mar;7(3):1291-7. doi: 10.1111/j.1743-6109.2009.01633.x. Epub 2009 Dec 1.
Loop electrosurgical excision procedure (LEEP) is an effective tool for management of cervical dysplasia. However, removal of a part of the cervix might have a negative impact on sexual function.
To examine the effect of LEEP on overall sexual satisfaction and other specific aspects of sexual function in women with cervical dysplasia.
Eighty-nine premenopausal women with cervical dysplasia who had undergone LEEP at least 3 months previously were interviewed once on post-LEEP follow-up visits with a questionnaire on pre- and post-procedural sexual function. Data on frequency of sexual intercourse, the presence of dysmenorrhea, dyspareunia, and postcoital bleeding were compared using the McNemar test. Data on specific aspects of sexual function rated by the 6-point Likert scale were analyzed using Wilcoxon signed ranks test.
The main outcome is the overall sexual intercourse satisfaction.
The mean age was 41.7 years. The median interval from LEEP to the time of interview was 29.3 weeks. The time of resumption of sexual intercourse after LEEP was 8.1 weeks on the average. The changes in the frequency of sexual intercourse, dysmenorrhea, and dyspareunia after LEEP were not statistically significant. The changes in overall satisfaction, vaginal elasticity, and orgasmic satisfaction appeared statistically significant (P < 0.05).
Having LEEP done along with other "non-surgical" parts of cervical pre-cancer management is associated with small but statistically significant decreases in overall sexual satisfaction, vaginal elasticity, and orgasmic satisfaction when interviewed near to the procedure at 29.3 weeks post-operation. However, the changes on other aspects of sexual function are insignificant. The LEEP procedure itself appears to have a minimal, if any, clinically important adverse effect on sexual function.
环形电切术（LEEP）是治疗宫颈发育不良的有效工具。然而，切除部分宫颈可能会对性功能产生负面影响。
研究 LEEP 对宫颈发育不良女性的整体性满意度和其他特定性功能方面的影响。
对 89 例至少在 3 个月前接受过 LEEP 治疗的绝经前宫颈发育不良女性进行了一次访谈，在 LEEP 后随访期间，她们使用问卷回答了术前和术后的性功能问题。使用 McNemar 检验比较性交频率、痛经、性交痛和性交后出血的存在情况。使用 Wilcoxon 符号秩检验分析 6 分 Likert 量表评定的特定性功能方面的数据。
主要结局是整体性交满意度。
平均年龄为 41.7 岁。LEEP 到访谈的中位时间间隔为 29.3 周。LEEP 后恢复性生活的平均时间为 8.1 周。LEEP 后性交频率、痛经和性交痛的变化无统计学意义。整体满意度、阴道弹性和性高潮满意度的变化有统计学意义（P <0.05）。
在进行 LEEP 治疗的同时进行其他“非手术”的宫颈癌前病变管理，与接近术后 29.3 周时进行采访时整体性满意度、阴道弹性和性高潮满意度的小但有统计学意义的下降有关。然而，其他性功能方面的变化则无统计学意义。LEEP 手术本身对性功能的影响最小，如果有影响的话，也没有临床意义。
