Miyazaki M, Hashimoto T, Fujino K, Goda T, Tayama M, Kuroda Y
Department of Pediatrics, University of Tokushima, School of Medicine, Japan.
Ann Neurol. 1991 Jan;29(1):97-9. doi: 10.1002/ana.410290118.
An 8-year-old boy with subacute sclerosing panencephalitis (SSPE) was treated with 1.0 to 3.0 x 10(6) IU human interferon alpha (IFN) by the intrathecal route weekly or fortnightly. Pronounced improvement of clinical and electroencephalographic findings were observed in a dose-dependent manner. Our patient raises hope that IFN can induce sustained remission in patients with SSPE.