亚急性硬化性全脑炎对鞘内注射α干扰素的明显反应
Apparent response of subacute sclerosing panencephalitis to intrathecal interferon alpha.
作者信息
Miyazaki M, Hashimoto T, Fujino K, Goda T, Tayama M, Kuroda Y
机构信息
Department of Pediatrics, University of Tokushima, School of Medicine, Japan.
出版信息
Ann Neurol. 1991 Jan;29(1):97-9. doi: 10.1002/ana.410290118.
PMID:1996885
Abstract
An 8-year-old boy with subacute sclerosing panencephalitis (SSPE) was treated with 1.0 to 3.0 x 10(6) IU human interferon alpha (IFN) by the intrathecal route weekly or fortnightly. Pronounced improvement of clinical and electroencephalographic findings were observed in a dose-dependent manner. Our patient raises hope that IFN can induce sustained remission in patients with SSPE.
摘要
一名患有亚急性硬化性全脑炎（SSPE）的8岁男孩，每周或每两周通过鞘内途径接受1.0至3.0×10⁶国际单位的人α干扰素（IFN）治疗。观察到临床和脑电图结果有明显改善，且呈剂量依赖性。我们的患者带来了希望，即干扰素能够诱导SSPE患者持续缓解。
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