Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Kowloon, Hong Kong, China.
Zoonoses Public Health. 2011 Feb;58(1):36-40. doi: 10.1111/j.1863-2378.2009.01286.x.
Elevated rates of methicillin-resistant Staphylococcus aureus (MRSA) carriage have been reported in veterinary personnel, suggesting an occupational colonization risk. Hong Kong veterinary personnel (n = 150) were sampled for coagulase-positive staphylococci (CPS) nasal colonization. Risk factors for colonization were assessed by questionnaire. Isolates were identified and antibiotic susceptibility determined. All CPS isolates were investigated for mecA carriage, SCCmec type and PVL genes. Two subjects were colonized with methicillin-resistant CPS: one with MRSA (spa type t002 (CC5), SCCmec type II) and one with methicillin-resistant Staphylococcus pseudintermedius (MRSP) (MLST type ST71, SCCmec type II-III). MLST type ST71 S. pseudintermedius strain is the predominant MRSP clone circulating in dogs in Europe and in Hong Kong. The low MR-CPS colonization rate may be associated with low levels of large animal exposure or low rates of MRSA colonization of companion animals in Hong Kong. Colonization with non-aureus CPS, which may cause human infection, must also be considered in veterinary personnel.
已报道兽医人员耐甲氧西林金黄色葡萄球菌（MRSA）携带率升高，表明存在职业定植风险。对 150 名香港兽医人员进行了凝固酶阳性葡萄球菌（CPS）鼻腔定植的抽样调查。通过问卷调查评估定植的危险因素。对分离株进行鉴定和药敏试验。对所有 CPS 分离株进行 mecA 携带、SCCmec 类型和 PVL 基因检测。有 2 名受试者定植了耐甲氧西林的 CPS：1 名是耐甲氧西林金黄色葡萄球菌（spa 型 t002（CC5），SCCmec 型 II），1 名是耐甲氧西林中间葡萄球菌（MRSP）（MLST 型 ST71，SCCmec 型 II-III）。MLST 型 ST71 中间葡萄球菌是欧洲和香港流行的主要 MRSP 克隆。MR-CPS 定植率低可能与大型动物接触水平低或香港伴侣动物中 MRSA 定植率低有关。兽医人员也必须考虑非金黄色葡萄球菌的定植，这可能会导致人类感染。
