Smith A D, Bharath A, Mallard C, Orr D, Smith K, Sutton J A, Vukmanich J, McCarty L S, Ozburn G W
Aquatic Toxicity Research Group, Lakehead University, Thunder Bay, Ontario, Canada.
Arch Environ Contam Toxicol. 1991 Jan;20(1):94-102. doi: 10.1007/BF01065334.
The acute toxicity (96-hr median lethal concentrations (LC50s) of ten chlorinated isomers of benzene, phenol, ethane, and ethylene to the American flagfish (Jordanella floridae) were determined in both static and flow-through systems. Chronic toxicity to embryo-larval fish was also estimated from hatching success and post-hatch survival as well as fry growth rates and survival. Maximum acceptable toxicant concentrations (MATC) were estimated where possible. In general, for both acute and chronic toxicity tests, the order of increasing relative toxicity based on the water-borne exposure concentrations was: chloroethanes, chloroethylenes, chlorobenzenes, and chlorophenols. Within groups, more highly chlorinated isomers were usually more toxic. The presence of suspended or colloidal 1,2,4,5-tetrachlorobenzene was observed in acute toxicity testing and affected toxicity estimates.
在静态和流水系统中测定了十种苯、苯酚、乙烷和乙烯的氯化异构体对美国旗鱼（Jordanella floridae）的急性毒性（96小时半数致死浓度（LC50））。还根据孵化成功率、孵化后存活率以及鱼苗生长率和存活率估算了对胚胎-幼体鱼的慢性毒性。在可能的情况下估算了最大可接受毒物浓度（MATC）。一般来说，对于急性和慢性毒性试验，基于水体暴露浓度，相对毒性增加的顺序为：氯乙烷、氯乙烯、氯苯和氯酚。在各基团内，氯化程度更高的异构体通常毒性更大。在急性毒性试验中观察到悬浮或胶体状的1,2,4,5-四氯苯的存在，并影响了毒性估算。
