Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, Minnesota.
Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina.
Fertil Steril. 2010 Sep;94(4):1500-1503. doi: 10.1016/j.fertnstert.2009.08.037. Epub 2009 Dec 6.
To examine racial diversity in clinical studies on uterine leiomyomas included in a review of evidence-based practice because of the disproportionate burden of fibroids in Black women.
Review of 106 studies cited in the Agency for Healthcare Research and Quality (AHRQ) report on uterine leiomyomas.
Academic medical centers.
PATIENT(S): None.
INTERVENTION(S): Estimation of the racial diversity of enrollment in studies on leiomyomas that did not report racial composition by two hypothetical models.
MAIN OUTCOME MEASURE(S): Representation of Black women in studies from the AHRQ report.
RESULT(S): Of the 106 analyzed studies, 81 studies did not report patients' race or ethnicity. Twenty-two of the 25 studies with reported race or ethnicity included Black participants. Analysis of studies reporting race and ethnicity, including studies specifically of African-American women, suggests that Black women comprise approximately half of all study participants. However, when estimating the proportion of Black women based on population demographics in each country, the representation of Black women in clinical leiomyoma studies appears to be closer to 15%.
CONCLUSION(S): Most studies on uterine leiomyomas cited in the AHRQ evidence-based report did not report participation by race or ethnicity.
检查纳入基于证据的实践综述的子宫肌瘤临床研究中的种族多样性，因为黑人女性患纤维瘤的负担不成比例。
对 AHRQ 子宫肌瘤报告中引用的 106 项研究进行回顾。
学术医疗中心。
无。
通过两种假设模型估计未报告种族构成的子宫肌瘤研究中纳入的种族多样性。
AHRQ 报告中研究中黑人女性的代表性。
在分析的 106 项研究中，81 项研究未报告患者的种族或民族。在 25 项报告了种族或民族的研究中，有 22 项纳入了黑人参与者。对报告种族和民族的研究（包括专门针对非裔美国女性的研究）进行分析表明，黑人女性约占所有研究参与者的一半。然而，根据每个国家的人口统计数据估计黑人女性的比例时，子宫肌瘤临床研究中黑人女性的代表性似乎接近 15%。
AHRQ 基于证据的报告中引用的大多数子宫肌瘤研究未报告种族或民族的参与情况。
