Gondivkar Shailesh M, Gadbail Amol R
Department of Oral Diagnosis, Medicine and Radiology, K M Shah Dental College and Hospital, Piparia, Vadodara, Gujarat, India.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Feb;109(2):e41-8. doi: 10.1016/j.tripleo.2009.08.043. Epub 2009 Dec 6.
Gorham-Stout syndrome is a very rare bone condition of unknown etiology. It is characterized by the spontaneous onset of bone resorption. Bones that previously appeared normal begin to resorb, partially or completely. Sometimes only a thin shell of cortical bone remains, and there is usually a little replacement by fibrous tissue. This process can continue for years but may stop spontaneously. Bone loss can occur in one bone or spread to soft tissue and adjacent bones. Although the disease may strike any of the bones of the body, it is more often recognized earlier when the calvarium and/or the mandible are involved. Because of its rarity, the disorder often goes unrecognized, and lack of agreement on how best to treat Gorham-Stout syndrome can delay the provision of treatment. We report the case of a 58-year-old man whose left body and ramus of mandible had disappeared as a result of massive osteolysis.
戈勒姆-斯托特综合征是一种病因不明的极为罕见的骨病。其特征是骨吸收自发发生。先前看似正常的骨骼开始部分或完全吸收。有时仅残留一层薄薄的皮质骨壳，通常会有少量纤维组织替代。这个过程可能持续数年，但也可能自行停止。骨质流失可发生在一块骨中，也可蔓延至软组织和相邻骨骼。尽管该疾病可能侵袭身体的任何骨骼，但当累及颅骨和/或下颌骨时，往往更早被发现。由于其罕见性，这种疾病常常未被识别，而且对于如何最佳治疗戈勒姆-斯托特综合征缺乏共识可能会延误治疗。我们报告一例58岁男性病例，其下颌骨左侧体部和升支因大量骨质溶解而消失。
