Dipartimento di Anestesiologia, Terapia Intensiva e Scienze Dermatologiche, Università degli Studi di Milano, Fondazione I.R.C.C.S., Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy.
Int J Infect Dis. 2010 Sep;14 Suppl 3:e230-2. doi: 10.1016/j.ijid.2009.07.024. Epub 2009 Dec 6.
Cutaneous leishmaniasis is an infection caused by protozoa belonging to the genus Leishmania. The disease is transmitted by sandflies. Reservoirs are represented by dogs, mice, rats, and wild rodents. Cutaneous leishmaniasis is usually characterized by a single, polymorphous lesion located in an uncovered area. We report a case of cutaneous leishmaniasis localized on the left upper eyelid in a 36-year-old woman. The disease was characterized by a single, asymptomatic nodule, which was clinically diagnosed as an inflammatory infundibular cyst. The lesion was excised surgically. Histopathological examination showed an inflammatory infiltrate consisting of lymphocytes, histiocytes, and plasma cells. Several Leishmania spp amastigotes were observed in the cytoplasm of macrophages. Culture examination on Novy-MacNeal-Nicolle medium was positive for Leishmania spp. PCR was positive for Leishmania infantum. No relapses were observed during follow-up (17 months). The purpose of this report is to emphasize the changeability of clinical presentation in cutaneous leishmaniasis.
皮肤利什曼病是一种由属于利什曼属的原生动物引起的感染。该疾病通过沙蝇传播。宿主为狗、鼠、大鼠和野生啮齿动物。皮肤利什曼病通常表现为单一的、多形性的病变，位于未覆盖的区域。我们报告了一例发生于 36 岁女性左侧上眼睑的皮肤利什曼病。该疾病表现为单一的、无症状的结节，临床上诊断为炎症性漏斗状囊肿。病变通过手术切除。组织病理学检查显示炎症浸润，由淋巴细胞、组织细胞和浆细胞组成。在巨噬细胞的细胞质中观察到几个利什曼原虫无鞭毛体。在 Novy-MacNeal-Nicolle 培养基上的培养检查对利什曼原虫呈阳性。PCR 对利什曼原虫婴儿亚种呈阳性。在随访期间（17 个月）未观察到复发。本报告的目的是强调皮肤利什曼病临床表现的多变性。
