Downs A R, Guzman R, Formichi M, Courbier R, Jausseran J M, Branchereau A, Juhan C, Chakfe N, King M, Guidoin R
Biomaterials Institute, St-François d'Assise Hospital, Laval University, Quebec.
Can J Surg. 1991 Feb;34(1):53-8.
To determine the etiology of anastomotic false aneurysms (AFAs), 26 textile graft specimens, removed because of AFA, were studied morphologically, histologically and by scanning electron microscopy. No cases of suture-related failures leading to AFA were found. Nine cases of frayed grafts were documented but were not the cause of AFA formation. In three cases, chemical degradation of the fibres, which may have been secondary to lipid infiltration, may have contributed to AFA formation. There were no cases of overt clinical infection, but the presence of bacteria was documented by scanning electron microscopy in 20 cases. The role of bacteria is not well defined, but they may be a factor in host arterial-wall degeneration as a cause for AFA formation.
为确定吻合口假性动脉瘤（AFA）的病因，对26个因AFA而切除的人工血管移植物标本进行了形态学、组织学及扫描电子显微镜研究。未发现因缝合相关失误导致AFA的病例。记录到9例人工血管磨损情况，但并非AFA形成的原因。3例中，纤维的化学降解（可能继发于脂质浸润）可能促使了AFA的形成。无明显临床感染病例，但扫描电子显微镜在20例中发现了细菌存在。细菌的作用尚不明确，但它们可能是宿主动脉壁退变导致AFA形成的一个因素。
